CHANGES IN NK CELLS OF CHILDREN WITH ACUTE LYMPHOCYTIC LEUKEMIA AT VARIOUS TREATMENT STAGES AND TERMS OF LONG‑TERM REMISSION

Dubej L.Y.

Peripheral blood NK cells from 87 children with acute lymphocytic leukemia (ALL) were studied in the period of program treatment and in various periods of long-term remission. The level of NK cells was found to be considerably decreased during the polychemotherapy of ALL. The population of NK cells tended to increase in a long-term (3 to 5 years) remission of ALL; however, their number was considerably lower compared to the control group suggesting about deficiency in the regeneration of this link of the immunity.