LIPOSOMAL DRUGS: APPROACH TO OVERCOME DRUG RESISTANCE TO CISPLATIN

Todor I.N.

The paper describes factors responsible for the drug resistance to cisplatin and characterizes liposomes as drug carriers. Literature is reviewed dealing with the application of liposomal forms of cisplatin to overcome drug resistance. Own experiments are presented where the liposomal form of cisplatin was used in animals with cisplatin-resistant Gurin’s carcinoma.