PARENCHYMATOUS-STROMAL INTERRELATIONS IN TUMORS AND THEIR SPECIFICS IN STOMACH CANCER OF INTESTINAL AND DIFFUSIVE TYPES

Vasilenko I.V., Kondratyuk R.B.

Modern literature data are discussed which suggest that cells of the neoplasm stroma release factors capable of fostering the invasion and metastasizing of tu- mor cells. It is established that tumor cells, in turn, are able to stimulate stroma cells to release these factors and even produce them in some cases. Specifics and charac- teristics of parenchymatous-stromal interrelations are analyzed in the main histological forms of stomach can- cer, i.e. intestinal and diffusive types. The data present- ed in the review can be used in morphological diagnos- tics of early stages, forecasting, and developing new ap- proaches to the treatment of oncologic patients.



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