BIOLOGICAL ACTIVITY OF NANOPARTICLES DEPENDING ON THEIR SIZE

Kundiev Y.I., Demetska O.V., Kucheruk T.K., Movchan V.O.

Basing on literature data and on the analysis of personal experimental material it is supposed that nanoparticles, occuring in the working zone air, can cause the increase of morbidity and mortality as a result of pathological changes in the respiratory and cardio- vascular systems. In particular, it is supposed that high rates of morbidity in electric welders is conditioned not only by toxicity of components of welding aerosols, but by their small particles, that can deeply penetrate into tissues. On the basis of the data of personal experimental studies the assumption is varified on the increase of biological activity of substances, presenting in the form of nanoparticles. In particular, it was established that the toxicity of substances of low toxicity (amorphous SіO2) increased substantially, when they are in the form of ultradisperse particles.