AROMATASE LETROMARA INHIBITOR BIOEQUIVALENCY ASSAY IN VITRO. THE STUDY OF PERMLABILITY OF CACO-2 CELLS TO REGIMENT

Reznikov A.G., Solov’ev A.I., Baula O.P., Tarasenko L.V., Margitich V.M.

Recently in vitro methods has been developed to confirm the bioequivalency of generic of Letromara (Letrozol, «Farmac», UA) that belong to the Class I of the Biopharmaceutical Classification System and exert both high solubility and permeability, to avoid further pharmacokinetic studies on healthy volunteers.