COMPLEX TREATMENT OF PATIENTS SUFFERING CHEMORESISTANT NON‑SMALL CELL LUNG CARCINOMA IN VIEW OF MOLECULAR GENETIC PROPERTIES OF THEIR TUMOR

Sukhoversha O.A.

Treatment results in 60 patients suffering stage ІІІА non‑small cell lung carcinoma (NSCLC) were analyzed in relation to molecular genetic properties of the tumor. High expression of Her2/neu combined with р53 mutation was found to serveasa marker of chemo‑resistance to NSCLC. Thes cheme of cytokinechemotherapy with the use of Navelbin was both theoretically substantiated and clinically tested inchemo‑resistant NSCLCwhichprovides for individualized approaches toward medical tactics in view of both tumor aggressiveness and molecular genetic factors in prognosis.