DIFFERENCE IN THE PROLIFERATIVE INDICES OF KI‑67 IN PATIENTS WITH MULTIPLE MENINGIOMA

Kondratyuk V.V., Kvasha M.S., Shmelyova G.A.

Histological structure and proliferative potential (Ki-67 expression level) in primary and secondary multiple meningiomas (MM) is studied and compared. It is shown that various tumor nodes of the same patient may have different histological patterns, varying level of anaplasia, and different proliferative activity suggesting a multifocal pattern of the tumor process. Development of secondary MMs is associated with increased atypia and Ki-67 expression levels.