ANTICANCER ACTIVITY OF CLASS OF MEDICINES «ERBISOL®» IN VITRO AND IN VIVO
It is shown that the class of drugs «Erbisol®» have cytotoxic activity in vitro in relation to the tumor cells-targets (there is a direct linear dependence of the concentration of the drug), as well as positive effects on lymphocytes, macrophages and hepatocytes. All the investigated substances have high therapeutic efficiency in mice with model tumor (solid form of sarcoma-37 and Ehrlich tumor), significantly slowing tumor growth (p < 0.05) and increasing the life span of animals (p < 0.05)). The best effect in all of the studied parameters was obtained by using the preparation Erbisol ULTRApharm, produced of chicken embryos (ChE). Preparations of Erbisol ULTRApharm (ChE), Erbisol (ChE), and the Erbisol (BF) can be effective cytostatics tumor cells, providing in the same doses beneficial effects on the cells of normal tissue.
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