TARGETED THERAPY IN NON-SMALL LUNG CANCER

Zakharychev V.D.

Lung cancer is the leading cause of cancer — related death among men and women in the world. Targeted therapies have been introduced that have improved standard chemotherapy approaches. Combining targeted therapies in specific patient populations with lung cancer may reduce the need for chemotherapy, and increased understanding of the targets involved in the pathogenesis of lung cancer may help to individualize drag therapy. There are essentially 2 targeted therapies currently available: erlotinib, which works by inhibiting the ATP-binding site of the epidermal growth factor receptor; and bevacizumab, which works by targeting the vascular endothelial growth factor. Bevacizumab, when used in combination, actually increases the efficacy of chemotherapy.



No comments » Add comment