CLINICO-HAEMATOLOGICAL FEATURES OF MOTION B-CELL NON-HODGKIN LYMPHOMA WITH ON A BACKGROUND HEPATITIS C VIRUS

Gaydukova S.N., Karnabeda O.A., Chyczewska E.

To do the comparative analysis of clinical motion Non-Hodgkin Lymphoma (NHL) with He- patitis C Virus (HCV) and without him with determina- of patients in the moment of establishment of diagnosis from 45 to 72 years. To all patients clinical research is conducted (general peripheral blood (PC) test, biochem- ical blood test, research of bone marrow (BM), computer tomografiya of organs of pectoral and abdominal cavity, imounofenopitouvannya BM and PC). The first group (n = 34) of research was made by patients with NHL with HCV, the second group (n = 33) — patients with NHL without HCV. This is also supported by more fre- quent involvement (> 1 site) in HCV-positive patients. Outcome of HCV-positive patients was poorer for overall survival and event-free survival. The short-term hepatic toxicity of chemotherapy was strongly increased among HCV-positive patients. Patients with NHL with HVC need more careful inspection, dynamic supervision af- ter the function of liver, conducting of dezintocsicatsiynoi therapy from the use of plazmaferezou and dezintocatsi- ynih solutions on a background conducting of specific therapy. After completion, patients it is necessary to ap- point antiviral therapy, what is possible duration of re- mission and survival will multiply on the whole. tion of subsequent tactic of medical treatment and super- vision after these patients. Under our supervision there were 67 (39 male and 28 female) patients with NHL. Age